Exosomes define a local and systemic communication network in healthy pancreas and pancreatic ductal adenocarcinoma

Exosomes define a local and systemic communication network in healthy pancreas and pancreatic ductal adenocarcinoma

Abstract Pancreatic ductal adenocarcinoma (PDAC), a lethal disease, requires a grasp of its biology for effective therapies. Exosomes, implicated in cancer, are poorly understood in living systems. Here we use the genetically engineered mouse model (ExoBow) to map the spatiotemporal distribution of...

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Bibliographic Details
Main Authors: Bárbara Adem, Nuno Bastos, Carolina F. Ruivo, Sara Sousa-Alves, Carolina Dias, Patrícia F. Vieira, Inês A. Batista, Bruno Cavadas, Dieter Saur, José C. Machado, Dawen Cai, Sonia A. Melo
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45753-7

Internet

https://doi.org/10.1038/s41467-024-45753-7

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