Chromatin accessibility landscapes of immune cells in rheumatoid arthritis nominate monocytes in disease pathogenesis

Chromatin accessibility landscapes of immune cells in rheumatoid arthritis nominate monocytes in disease pathogenesis

Abstract Background Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that involves a variety of cell types. However, how the epigenetic dysregulations of peripheral immune cells contribute to the pathogenesis of RA still remains largely unclear. Results Here, we analysed the genom...

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Bibliographic Details
Main Authors: Dandan Zong, Beibei Huang, Young Li, Yichen Lu, Nan Xiang, Chuang Guo, Qian Liu, Qing Sha, Pengcheng Du, Qiaoni Yu, Wen Zhang, Pengfei Cai, Yanping Sun, Jinhui Tao, Xiaomei Li, Shanbao Cai, Kun Qu
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Biology
Subjects:
Rheumatoid arthritis (RA)
Chromatin dysregulation
Monocytes
C-reactive protein
FRA2
Online Access:https://doi.org/10.1186/s12915-021-01011-6

Internet

https://doi.org/10.1186/s12915-021-01011-6

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