Modification of the Release of Poorly Soluble Sulindac with the APTES-Modified SBA-15 Mesoporous Silica

Modification of the Release of Poorly Soluble Sulindac with the APTES-Modified SBA-15 Mesoporous Silica

The effectiveness of oral drug administration is related to the solubility of a drug in the gastrointestinal tract and its ability to penetrate the biological membranes. As most new drugs are poorly soluble in water, there is a need to develop novel drug carriers that improve the dissolution rate an...

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Bibliographic Details
Main Authors: Adrianna Dadej, Aneta Woźniak-Braszak, Paweł Bilski, Hanna Piotrowska-Kempisty, Małgorzata Józkowiak, Małgorzata Geszke-Moritz, Michał Moritz, Daniela Dadej, Anna Jelińska
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceutics
Subjects:
mesoporous silica
SBA-15
dissolution rate
drug delivery system
sulindac
physicochemical techniques
Online Access:https://www.mdpi.com/1999-4923/13/10/1693

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https://www.mdpi.com/1999-4923/13/10/1693

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