Molecular dynamic and bioinformatic studies of metformin-induced ACE2 phosphorylation in the presence of different SARS-CoV-2 S protein mutations

The SARS-CoV-2 infection activates host kinases and causes high phosphorylation in both the host and the virus. There were around 70 phosphorylation sites found in SARS-CoV-2 viral proteins. Besides, almost 15,000 host phosphorylation sites were found in SARS-CoV-2-infected cells. COVID-19 is though...

Full description

Bibliographic Details
Main Authors: Amr Ahmed El-Arabey, Mohnad Abdalla, Adel Rashad Abd-Allah, Hanin.S. Marenga, Yosra Modafer, Abeer S. Aloufi
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Saudi Journal of Biological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X23001444