pCR and 2-Year Disease-Free Survival: A Combination of the Two Endpoints as a New Classification for Locally Advanced Rectal Cancer Patients—An Updated Pooled Analysis of Eleven International Randomized Trials

LARC is managed by multimodal treatments whose intensity can be highly modulated. In this context, we need surrogate endpoints to help predict long-term outcomes and better personalize treatments. A previous study identified 2yDFS as a stronger predictor of OS than pCR in LARC patients undergoing ne...

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Main Authors: Maria Antonietta Gambacorta, Giuditta Chiloiro, Carlotta Masciocchi, Silvia Mariani, Angela Romano, Alessandra Gonnelli, Jean-Pierre Gerard, Samuel Ngan, Claus Rödel, Krzysztof Bujko, Robert Glynne-Jones, Johan van Soest, Andre Dekker, Andrea Damiani, Vincenzo Valentini
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/12/3209