Cadmium exposure activates the PI3K/AKT signaling pathway through miRNA-21, induces an increase in M1 polarization of macrophages, and leads to fibrosis of pig liver tissue

Cadmium exposure activates the PI3K/AKT signaling pathway through miRNA-21, induces an increase in M1 polarization of macrophages, and leads to fibrosis of pig liver tissue

Cadmium (Cd) is a toxic substance that pollutes the environment with multiple organs. Long-term exposure to Cd can cause fibrosis in the lungs and other organs of animal body. This article explored the effects of subacute Cd exposure on pig liver fibrosis, as well as the polarization of microRNA (mi...

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Bibliographic Details
Main Authors: Wei Cui, Sitong Zhou, YuLin Wang, Xu Shi, Honggui Liu
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cadmium
Pig Liver
M1/M2 imbalance
TGF-β/PI3K/AKT
Fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321011271

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http://www.sciencedirect.com/science/article/pii/S0147651321011271

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