Isoprostanoid Plasma Levels Are Relevant to Cerebral Adrenoleukodystrophy Disease

Isoprostanoid Plasma Levels Are Relevant to Cerebral Adrenoleukodystrophy Disease

Cerebral adrenoleukodystrophy (ALD) is a rare neuroinflammatory disorder characterized by progressive demyelination. Mutations within the <i>ABCD1</i> gene result in very long-chain fatty acid (VLCFA) accumulation within the peroxisome, particularly in the brain. While this VLCFA accumul...

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Bibliographic Details
Main Authors: Cinzia Signorini, Claudio De Felice, Thierry Durand, Jean-Marie Galano, Camille Oger, Silvia Leoncini, Joussef Hayek, Jetty Chung-Yung Lee, Troy C. Lund, Paul J. Orchard
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Life
Subjects:
cerebral adrenoleukodystrophy
fatty acids
hematopoietic stem cell transplantation
isoprostanes
N-acetyl-L-cysteine
neuroprostanes
Online Access:https://www.mdpi.com/2075-1729/12/2/146

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https://www.mdpi.com/2075-1729/12/2/146

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