Arginine methylation of PPP1CA by CARM1 regulates glucose metabolism and affects osteogenic differentiation and osteoclastic differentiation

Arginine methylation of PPP1CA by CARM1 regulates glucose metabolism and affects osteogenic differentiation and osteoclastic differentiation

Abstract Background The imbalance between osteoblasts and osteoclasts may lead to osteoporosis. Osteoblasts and osteoclasts have different energy requirements, with aerobic glycolysis being the prominent metabolic feature of osteoblasts, while osteoclast differentiation and fusion are driven by oxid...

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Bibliographic Details
Main Authors: Lu Zhang, Guangjun Jiao, Yunhao You, Xiang Li, Jincheng Liu, Zhenqian Sun, Qinghui Li, Zihan Dai, Jinlong Ma, Hongming Zhou, Gang Li, Chunyang Meng, Yunzhen Chen
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Clinical and Translational Medicine
Subjects:
CARM1
glucose metabolism
osteoclast differentiation
osteogenic differentiation
osteoporosis
Online Access:https://doi.org/10.1002/ctm2.1369

Internet

https://doi.org/10.1002/ctm2.1369

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