PCC0208057 as a small molecule inhibitor of TRPC6 in the treatment of prostate cancer

PCC0208057 as a small molecule inhibitor of TRPC6 in the treatment of prostate cancer

Prostate cancer (PCa) is a common malignant tumor, whose morbidity and mortality keep the top three in the male-related tumors in developed countries. Abnormal ion channels, such as transient receptor potential canonical 6 (TRPC6), are reported to be involved in the carcinogenesis and progress of pr...

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Bibliographic Details
Main Authors: Yingjie Wei, Min Li, Yuemiao Hu, Jing Lu, Lin Wang, Qikun Yin, Xuechuan Hong, Jingwei Tian, Hongbo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Pharmacology
Subjects:
prostate cancer
TRPC6 channel
TRPC6 small molecule inhibitor
cycle arrest
growth inhibition
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1352373/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1352373/full

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