Heat shock factor 1 directly regulates transsulfuration pathway to promote prostate cancer proliferation and survival

Heat shock factor 1 directly regulates transsulfuration pathway to promote prostate cancer proliferation and survival

Abstract There are limited therapeutic options for patients with advanced prostate cancer (PCa). We previously found that heat shock factor 1 (HSF1) expression is increased in PCa and is an actionable target. In this manuscript, we identify that HSF1 regulates the conversion of homocysteine to cysta...

Full description

Bibliographic Details
Main Authors: J. Spencer Hauck, David Moon, Xue Jiang, Mu-En Wang, Yue Zhao, Lingfan Xu, Holly Quang, William Butler, Ming Chen, Everardo Macias, Xia Gao, Yiping He, Jiaoti Huang
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05727-9

Internet

https://doi.org/10.1038/s42003-023-05727-9

Similar Items