Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency.

The multi-subunit mammalian Mediator complex acts as an integrator of transcriptional regulation by RNA Polymerase II, and has emerged as a master coordinator of development and cell fate determination. We previously identified the Mediator subunit, MED28, as a cytosolic binding partner of merlin, t...

Full description

Bibliographic Details
Main Authors: Lin Li, Ryan M Walsh, Vilas Wagh, Marianne F James, Roberta L Beauchamp, Yuh-Shin Chang, James F Gusella, Konrad Hochedlinger, Vijaya Ramesh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4596692?pdf=render