Analytical Validation of a Spiral Microfluidic Chip with Hydrofoil-Shaped Pillars for the Enrichment of Circulating Tumor Cells

Analytical Validation of a Spiral Microfluidic Chip with Hydrofoil-Shaped Pillars for the Enrichment of Circulating Tumor Cells

The isolation of circulating tumor cells (CTCs) from peripheral blood with high efficiency remains a challenge hindering the utilization of CTC enrichment methods in clinical practice. Here, we propose a microfluidic channel design for the size-based hydrodynamic enrichment of CTCs from blood in an...

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Bibliographic Details
Main Authors: Begum Sen-Dogan, Mehmet Alper Demir, Buket Sahin, Ender Yildirim, Gizem Karayalcin, Sebnem Sahin, Ege Mutlu, Taylan Berkin Toral, Ebru Ozgur, Ozge Zorlu, Haluk Kulah
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biosensors
Subjects:
microfluidic channel
computational fluid dynamics
circulating tumor cell (CTC) separation
inertial hydrodynamics
Online Access:https://www.mdpi.com/2079-6374/13/10/938

Internet

https://www.mdpi.com/2079-6374/13/10/938

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