Unlike Glycerophosphocholine or Choline Chloride, Dietary Phosphatidylcholine Does Not Increase Plasma Trimethylamine-<i>N</i>-Oxide Levels in Sprague-Dawley Rats

Choline, betaine, and L-carnitine are transformed into trimethylamine (TMA) by gut microbiota, absorbed into the liver, and oxidized into trimethylamine-<i>N</i>-oxide (TMAO) by flavin-containing monooxygenases. Elevated TMAO levels may negatively affect human health. As phosphatidylchol...

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Bibliographic Details
Main Authors: Bungo Shirouchi, Ayano Fukuda, Taiki Akasaka
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/1/64