Single‐cell transcriptomics reveals immune response of intestinal cell types to viral infection

Single‐cell transcriptomics reveals immune response of intestinal cell types to viral infection

Abstract Human intestinal epithelial cells form a primary barrier protecting us from pathogens, yet only limited knowledge is available about individual contribution of each cell type to mounting an immune response against infection. Here, we developed a framework combining single‐cell RNA‐Seq and h...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Sergio Triana, Megan L Stanifer, Camila Metz‐Zumaran, Mohammed Shahraz, Markus Mukenhirn, Carmon Kee, Clara Serger, Ronald Koschny, Diana Ordoñez‐Rueda, Malte Paulsen, Vladimir Benes, Steeve Boulant, Theodore Alexandrov
Format: Artikel
Sprache:English
Veröffentlicht: Springer Nature 2021-07-01
Schriftenreihe:Molecular Systems Biology
Schlagworte:
astrovirus
immune response
intestinal epithelial cells
organoids
single‐cell transcriptomics
Online Zugang:https://doi.org/10.15252/msb.20209833

Online

https://doi.org/10.15252/msb.20209833

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