Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis

Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis

Mortality and morbidity from tuberculous meningitis (TBM) are common, primarily due to inflammatory response to Mycobacterium tuberculosis infection, yet the underlying mechanisms remain poorly understood. We aimed to uncover genes and pathways associated with TBM pathogenesis and mortality, and det...

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Bibliographic Details
Main Authors: Hoang Thanh Hai, Le Thanh Hoang Nhat, Trinh Thi Bich Tram, Do Dinh Vinh, Artika P Nath, Joseph Donovan, Nguyen Thi Anh Thu, Dang Van Thanh, Nguyen Duc Bang, Dang Thi Minh Ha, Nguyen Hoan Phu, Ho Dang Trung Nghia, Le Hong Van, Michael Inouye, Guy E Thwaites, Nguyen Thuy Thuong Thuong
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-10-01
Series:eLife
Subjects:
tuberculous meningitis
mortality
pathogenesis
prognostic
whole blood RNA sequencing
Online Access:https://elifesciences.org/articles/92344

Internet

https://elifesciences.org/articles/92344

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