Epigenetic reshaping through damage: promoting cell fate transition by BrdU and IdU incorporation
Abstract Background Thymidine analogs have long been recognized for their ability to randomly incorporate into DNA. However, the precise mechanisms through which thymidine analogs facilitate cell fate transition remains unclear. Results Here, we discovered a strong correlation between the dosage dep...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
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Series: | Cell & Bioscience |
Online Access: | https://doi.org/10.1186/s13578-024-01192-x |