Akt: a key transducer in cancer

Abstract Growth factor signaling plays a pivotal role in diverse biological functions, such as cell growth, apoptosis, senescence, and migration and its deregulation has been linked to various human diseases. Akt kinase is a central player transmitting extracellular clues to various cellular compart...

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Bibliographic Details
Main Authors: Pei-Jane Tsai, Yi-Hsin Lai, Rajesh Kumar Manne, Yau-Sheng Tsai, Dos Sarbassov, Hui-Kuan Lin
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Biomedical Science
Subjects:
Online Access:https://doi.org/10.1186/s12929-022-00860-9