Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures

Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures

Absence seizures impair consciousness by an unknown neuronal mechanism. Here, the authors find that a rat absence seizure model’s behavior and hemodynamics recapitulate previously reported characteristics of human absence seizures, and uncover four distinct patterns of neuronal activity in cortex an...

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Bibliographic Details
Main Authors: Cian McCafferty, Benjamin F. Gruenbaum, Renee Tung, Jing-Jing Li, Xinyuan Zheng, Peter Salvino, Peter Vincent, Zachary Kratochvil, Jun Hwan Ryu, Aya Khalaf, Kohl Swift, Rashid Akbari, Wasif Islam, Prince Antwi, Emily A. Johnson, Petr Vitkovskiy, James Sampognaro, Isaac G. Freedman, Adam Kundishora, Antoine Depaulis, François David, Vincenzo Crunelli, Basavaraju G. Sanganahalli, Peter Herman, Fahmeed Hyder, Hal Blumenfeld
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35535-4

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https://doi.org/10.1038/s41467-022-35535-4

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