DNA Holliday Junction: History, Regulation and Bioactivity

DNA Holliday Junction: History, Regulation and Bioactivity

DNA Holliday junction (HJ) is a four-way stranded DNA intermediate that formed in replication fork regression, homology-dependent repair and mitosis, performing a significant role in genomic stability. Failure to remove HJ can induce an acceptable replication fork stalling and DNA damage in normal c...

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Bibliographic Details
Main Authors: Qinqin Song, Yuemiao Hu, Anqi Yin, Hongbo Wang, Qikun Yin
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
DNA Holliday junction
HJ nuclease
DNA damage
chromosomal aberration
HJ-targeting ligand
Online Access:https://www.mdpi.com/1422-0067/23/17/9730

Internet

https://www.mdpi.com/1422-0067/23/17/9730

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