Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis.

Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis.

Hippocampal sclerosis (HS) is a common pathological finding in patients with temporal lobe epilepsy (TLE) and is associated with altered expression of genes controlling neuronal excitability, glial function, neuroinflammation and cell death. MicroRNAs (miRNAs), a class of small non-coding RNAs, func...

Full description

Bibliographic Details
Main Authors: Ross C McKiernan, Eva M Jimenez-Mateos, Isabella Bray, Tobias Engel, Gary P Brennan, Takanori Sano, Zuzanna Michalak, Catherine Moran, Norman Delanty, Michael Farrell, Donncha O'Brien, Robert Meller, Roger P Simon, Raymond L Stallings, David C Henshall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3352899?pdf=render

Internet

http://europepmc.org/articles/PMC3352899?pdf=render

Similar Items