The Ifng antisense RNA 1 (IFNG-AS1) and growth arrest-specific transcript 5 (GAS5) are novel diagnostic and prognostic markers involved in childhood ITP

The Ifng antisense RNA 1 (IFNG-AS1) and growth arrest-specific transcript 5 (GAS5) are novel diagnostic and prognostic markers involved in childhood ITP

Background/aim:IFNG-AS1 is a long noncoding RNA that works as an enhancer for the Interferon-gamma (IFN-γ) transcript. GAS5 (growth arrest-specific 5) is a lncRNA that is associated with glucocorticoid resistance. Aberrant expressions of IFNG-AS1 and GAS5 are directly linked to numerous autoimmune d...

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Bibliographic Details
Main Authors: Marwa A. Ali, Sherin Khamis Hussein, Abeer A. Khalifa, Amani M. El Amin Ali, Marwa S. Farhan, Amal A. Ibrahim Amin, Esam Ali Mohamed
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
IFNG-AS1
GAS5
childhood ITP
qRT-PCR
diagnosis
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.1007347/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.1007347/full

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