Operating characteristics of unequal allocation ratios in platform trials with the staggered addition of drugs using binary endpoints
Background: One recommendation for the allocation ratio between multiple drugs and a shared placebo control group in platform trials (PTs) is to use a k:1 allocation ratio for the placebo group relative to the drug group, where k is the number of drug groups with ongoing patient enrollment during th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-04-01
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| Series: | Contemporary Clinical Trials Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451865425000249 |