SENSITIVILITY PROFILE HEP-G2 AS A MODEL OF CYTOTOXIC ACTIVITY DETERMINATION OF BIOACTIVATED XENOBIOTICS VIA CYP <sub>450</sub>
Several methodologies have been proposed in order to establish anticancer action, mainly focused on in vitro cytotoxicity valuation on neoplasic cell lines derived from human cancer. However, most of these cell lines are metabolically incompetent, restricting model sensibility and generating false n...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Universidad de Antioquia
2009-07-01
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| Series: | Vitae |
| Subjects: | |
| Online Access: | https://revistas.udea.edu.co/index.php/vitae/article/view/1933 |