Zebrafish Avatars of rectal cancer patients validate the radiosensitive effect of metformin

Zebrafish Avatars of rectal cancer patients validate the radiosensitive effect of metformin

Neoadjuvant chemoradiation (nCRT) followed by surgery represents the standard of care in patients with locally advanced rectal cancer. Increasing radiotherapy (RT) doses and chemotherapy cycles with 5FU have been associated with increased rates of complete response, however these strategies imply si...

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Bibliographic Details
Main Authors: Bruna Costa, Laura M. Fernandez, Oriol Parés, Ricardo Rio-Tinto, Inês Santiago, Mireia Castillo-Martin, Amjad Parvaiz, Rita Fior
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
rectal cancer
metformin
radiotherapy
neoadjuvant chemoradiation
zebrafish Avatars
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.862889/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.862889/full

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