Traumatic brain injury-induced dysregulation of the circadian clock.

Circadian rhythm disturbances are frequently reported in patients recovering from traumatic brain injury (TBI). Since circadian clock output is mediated by some of the same molecular signaling cascades that regulate memory formation (cAMP/MAPK/CREB), cognitive problems reported by TBI survivors may...

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Bibliographic Details
Main Authors: Deborah R Boone, Stacy L Sell, Maria-Adelaide Micci, Jeanna M Crookshanks, Margaret Parsley, Tatsuo Uchida, Donald S Prough, Douglas S DeWitt, Helen L Hellmich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23056261/pdf/?tool=EBI