DnaK Functions as a Central Hub in the E. coli Chaperone Network

Cellular chaperone networks prevent potentially toxic protein aggregation and ensure proteome integrity. Here, we used Escherichia coli as a model to understand the organization of these networks, focusing on the cooperation of the DnaK system with the upstream chaperone Trigger factor (TF) and the...

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Bibliographic Details
Main Authors: Giulia Calloni, Taotao Chen, Sonya M. Schermann, Hung-chun Chang, Pierre Genevaux, Federico Agostini, Gian Gaetano Tartaglia, Manajit Hayer-Hartl, F. Ulrich Hartl
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124711000179