Role of inflammasomes in multiple sclerosis and their potential as therapeutic targets

Role of inflammasomes in multiple sclerosis and their potential as therapeutic targets

Abstract Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS), and it remains the most common immune-mediated disorder affecting the CNS. While the cause of MS is unclear, the underlying pathomechanisms are thought to be either destruction by autoimmune T cells or d...

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Bibliographic Details
Main Authors: Vaidya Govindarajan, Juan Pablo de Rivero Vaccari, Robert W. Keane
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Neuroinflammation
Subjects:
Inflammasome
multiple sclerosis
EAE
caspase-1
IL-1β
Online Access:http://link.springer.com/article/10.1186/s12974-020-01944-9

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http://link.springer.com/article/10.1186/s12974-020-01944-9

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