Association of novel DNAH11 variants with asthenoteratozoospermia lead to male infertility

Association of novel DNAH11 variants with asthenoteratozoospermia lead to male infertility

Abstract Background Bi-allelic variants in DNAH11 have been identified as causative factors in Primary Ciliary Dyskinesia, leading to abnormal respiratory cilia. Nonetheless, the specific impact of these variants on human sperm flagellar and their involvement in male infertility remain largely unkno...

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Bibliographic Details
Main Authors: Senzhao Guo, Dongdong Tang, Yuge Chen, Hui Yu, Meng Gu, Hao Geng, Jiajun Fang, Baoyan Wu, Lewen Ruan, Kuokuo Li, Chuan Xu, Yang Gao, Qing Tan, Zongliu Duan, Huan Wu, Rong Hua, Rui Guo, Zhaolian Wei, Ping Zhou, Yuping Xu, Yunxia Cao, Xiaojin He, Yanwei Sha, Mingrong Lv
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Human Genomics
Subjects:
Male infertility
Asthenoteratozoospermia
WES
DNAH11
ICSI
Online Access:https://doi.org/10.1186/s40246-024-00658-w

Internet

https://doi.org/10.1186/s40246-024-00658-w

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