Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane

Abstract Bacterial competition is a significant driver of toxin polymorphism, which allows continual compensatory evolution between toxins and the resistance developed to overcome their activity. Bacterial Rearrangement hot spot (Rhs) proteins represent a widespread example of toxin polymorphism. He...

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Bibliographic Details
Main Authors: Amaia González-Magaña, Igor Tascón, Jon Altuna-Alvarez, María Queralt-Martín, Jake Colautti, Carmen Velázquez, Maialen Zabala, Jessica Rojas-Palomino, Marité Cárdenas, Antonio Alcaraz, John C. Whitney, Iban Ubarretxena-Belandia, David Albesa-Jové
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43585-5