Identification of Combinations of Protein Kinase C Activators and Histone Deacetylase Inhibitors that Potently Reactivate Latent HIV

Combination antiretroviral therapy (cART) is successful in maintaining undetectable levels of HIV in the blood; however, the persistence of latent HIV reservoirs has become the major barrier for a HIV cure. Substantial efforts are underway in finding the best latency-reversing agents (LRAs) to purge...

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Bibliographic Details
Main Authors: Francesca Curreli, Shahad Ahmed, Sofia M. Benedict Victor, Asim K. Debnath
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/6/609