Biologic TNF-alpha inhibitors in the treatment of Stevens-Johnson syndrome and toxic epidermal necrolysis: a systemic review

Background: Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) is one of severe cutaneous adverse reactions with low morbidity but high mortality. Different systemic immunomodulating treatments are proposed but still remain controversial. Tumor necrosis factor (TNF)-alpha is long thou...

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Bibliographic Details
Main Authors: Shan Zhang, Shunli Tang, Sheng Li, Yunlei Pan, Yingguo Ding
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:http://dx.doi.org/10.1080/09546634.2019.1577548