NOX4 regulates TGFβ‐induced proliferation and self‐renewal in glioblastoma stem cells

NOX4 regulates TGFβ‐induced proliferation and self‐renewal in glioblastoma stem cells

Glioblastoma (GBM) is the most aggressive and common glioma subtype, with a median survival of 15 months after diagnosis. Current treatments have limited therapeutic efficacy; thus, more effective approaches are needed. The glioblastoma tumoural mass is characterised by a small cellular subpopulatio...

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Bibliographic Details
Main Authors: Pedro García‐Gómez, Irene Golán, Mahsa S. Dadras, Artur Mezheyeuski, Claudia Bellomo, Kalliopi Tzavlaki, Anita Morén, Jordi Carreras‐Puigvert, Laia Caja
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Molecular Oncology
Subjects:
glioblastoma
NOX4
proliferation
ROS
stem cells
TGFβ
Online Access:https://doi.org/10.1002/1878-0261.13200

Internet

https://doi.org/10.1002/1878-0261.13200

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