Schlafen 12 Is Prognostically Favorable and Reduces C-Myc and Proliferation in Lung Adenocarcinoma but Not in Lung Squamous Cell Carcinoma

Schlafen 12 Is Prognostically Favorable and Reduces C-Myc and Proliferation in Lung Adenocarcinoma but Not in Lung Squamous Cell Carcinoma

Schlafen 12 (SLFN12) is an intermediate human Schlafen that induces differentiation in enterocytes, prostate, and breast cancer. We hypothesized that SLFN12 influences lung cancer biology. We investigated survival differences in high versus low SLFN12-expressing tumors in two databases. We then aden...

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Bibliographic Details
Main Authors: Sarmad Al-Marsoummi, Jonathan Pacella, Kaylee Dockter, Matthew Soderberg, Sandeep K. Singhal, Emilie E. Vomhof-DeKrey, Marc D. Basson
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
Schlafen 12
c-myc
lung adenocarcinoma
lung squamous cell carcinoma
non-small cell lung cancer
Online Access:https://www.mdpi.com/2072-6694/12/10/2738

Internet

https://www.mdpi.com/2072-6694/12/10/2738

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