A mathematical investigation of polyaneuploid cancer cell memory and cross-resistance in state-structured cancer populations

A mathematical investigation of polyaneuploid cancer cell memory and cross-resistance in state-structured cancer populations

Abstract The polyaneuploid cancer cell (PACC) state promotes cancer lethality by contributing to survival in extreme conditions and metastasis. Recent experimental evidence suggests that post-therapy PACC-derived recurrent populations display cross-resistance to classes of therapies with independent...

Bibliográfalaš dieđut
Váldodahkkit:	Anuraag Bukkuri, Kenneth J. Pienta, Robert H. Austin, Emma U. Hammarlund, Sarah R. Amend, Joel S. Brown
Materiálatiipa:	Artihkal
Giella:	English
Almmustuhtton:	Nature Portfolio 2023-09-01
Ráidu:	Scientific Reports
Liŋkkat:	https://doi.org/10.1038/s41598-023-42368-8

Geahča maid

A life history model of the ecological and evolutionary dynamics of polyaneuploid cancer cells
Dahkki: Anuraag Bukkuri, et al.
Almmustuhtton: (2022-08-01)

Polyaneuploid Cancer Cell Dormancy: Lessons From Evolutionary Phyla
Dahkki: Laurie G. Kostecka, et al.
Almmustuhtton: (2021-07-01)

Stochastic models of Mendelian and reverse transcriptional inheritance in state-structured cancer populations
Dahkki: Anuraag Bukkuri, et al.
Almmustuhtton: (2022-07-01)

The contribution of evolvability to the eco‐evolutionary dynamics of competing species
Dahkki: Anuraag Bukkuri, et al.
Almmustuhtton: (2023-10-01)

Poly‐aneuploid cancer cells promote evolvability, generating lethal cancer
Dahkki: Kenneth J. Pienta, et al.
Almmustuhtton: (2020-08-01)

Integrating eco‐evolutionary dynamics into matrix population models for structured populations: Discrete and continuous frameworks
Dahkki: Anuraag Bukkuri, et al.
Almmustuhtton: (2023-06-01)

Cell types or cell states? An investigation of adrenergic and mesenchymal cell phenotypes in neuroblastoma
Dahkki: Anuraag Bukkuri, et al.
Almmustuhtton: (2024-12-01)

GLUT1 production in cancer cells: a tragedy of the commons
Dahkki: Anuraag Bukkuri, et al.
Almmustuhtton: (2022-06-01)

Optimal control analysis of combined chemotherapy-immunotherapy treatment regimens in a PKPD cancer evolution model
Dahkki: Anuraag Bukkuri
Almmustuhtton: (2020-03-01)

Evolutionary Game Theory: Darwinian Dynamics and the <i>G</i> Function Approach
Dahkki: Anuraag Bukkuri, et al.
Almmustuhtton: (2021-09-01)

Viewing Cancer Through the Lens of Corruption: Using Behavioral Ecology to Understand Cancer
Dahkki: Anuraag Bukkuri, et al.
Almmustuhtton: (2021-07-01)

The impact of infected T lymphocyte burst rate and viral shedding rate on optimal treatment scheduling in a human immunodeficiency virus infection
Dahkki: Anuraag Bukkuri
Almmustuhtton: (2020-09-01)

Cancer Cells and M2 Macrophages: Cooperative Invasive Ecosystem Engineers
Dahkki: Kayla V. Myers, et al.
Almmustuhtton: (2020-03-01)

Coupled Source-Sink Habitats Produce Spatial and Temporal Variation of Cancer Cell Molecular Properties as an Alternative to Branched Clonal Evolution and Stem Cell Paradigms
Dahkki: Jessica J. Cunningham, et al.
Almmustuhtton: (2021-07-01)

Escherichia coli survival in response to ciprofloxacin antibiotic stress correlates with increased nucleoid length and effective misfolded protein management
Dahkki: George Butler, et al.
Almmustuhtton: (2023-08-01)

Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment
Dahkki: Kayla V. Myers, et al.
Almmustuhtton: (2019-05-01)

The Role of αvβ3 in Prostate Cancer Progression
Dahkki: Carlton R. Cooper, et al.
Almmustuhtton: (2002-01-01)

What’s Done is Done: Verb Aspect and Verbatim Memory
Dahkki: Meghan Salomon-Amend, et al.
Almmustuhtton: (2017-09-01)

RNA profiling of circulating tumor cells systemically captured from diagnostic leukapheresis products in prostate cancer patients
Dahkki: Liang Dong, et al.
Almmustuhtton: (2022-12-01)

Exploration of drug resistance mechanisms in triple negative breast cancer cells using a microfluidic device and patient tissues
Dahkki: Wanyoung Lim, et al.
Almmustuhtton: (2024-03-01)

Nuclear morphology predicts cell survival to cisplatin chemotherapy
Dahkki: Chi-Ju Kim, et al.
Almmustuhtton: (2023-08-01)

Detection and Isolation of Circulating Tumor Cells in Urologic Cancers: A Review
Dahkki: Robert D. Loberg, et al.
Almmustuhtton: (2004-07-01)

MIM, a Potential Metastasis Suppressor Gene in Bladder Cancer
Dahkki: Young-Goo Lee, et al.
Almmustuhtton: (2002-01-01)

Oligometastatic Prostate Cancer to the Navicular Bone: Case Report
Dahkki: Diane K. Reyes, et al.
Almmustuhtton: (2015-05-01)

CCL2 Is a Negative Regulator of AMP-Activated Protein Kinase to Sustain mTOR Complex-1 Activation, Survivin Expression, and Cell Survival in Human Prostate Cancer PC3 Cells
Dahkki: Hernan Roca, et al.
Almmustuhtton: (2009-12-01)

Cancer dormancy and criticality from a game theory perspective
Dahkki: Amy Wu, et al.
Almmustuhtton: (2018-01-01)

Metastatic prostate cancer remains incurable, why?
Dahkki: Liang Dong, et al.
Almmustuhtton: (2019-01-01)

Tumour tissue‐derived small extracellular vesicles reflect molecular subtypes of bladder cancer
Dahkki: Liang Dong, et al.
Almmustuhtton: (2024-02-01)

Targeting interleukin 4 receptor alpha on tumor-associated macrophages reduces the pro-tumor macrophage phenotype
Dahkki: Amber E. de Groot, et al.
Almmustuhtton: (2022-10-01)

Mathematical model reveals the role of memory CD8 T cell populations in recall responses to influenza.
Dahkki: Veronika eZarnitsyna, et al.
Almmustuhtton: (2016-05-01)

Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer
Dahkki: Johnston, M, et al.
Almmustuhtton: (2007)

Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer
Dahkki: Johnston, M, et al.
Almmustuhtton: (2007)

Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer.
Dahkki: Johnston, MD, et al.
Almmustuhtton: (2007)

Mathematical characterization of population dynamics in breast cancer cells treated with doxorubicin
Dahkki: Emily Y. Yang, et al.
Almmustuhtton: (2022-09-01)

Obituary for Donald S. Coffey: Remembering a pioneer in the field of prostate cancer research. (1932–2017)
Dahkki: Shawn E. Lupold, et al.
Almmustuhtton: (2018-01-01)

Activation of Urokinase Plasminogen Activator and Its Receptor Axis Is Essential for Macrophage Infiltration in a Prostate Cancer Mouse Model
Dahkki: Jian Zhang, et al.
Almmustuhtton: (2011-01-01)

You Win Some, You Lose Some: Compensating the Loss of Green Space in Cities Considering Heterogeneous Population Characteristics
Dahkki: Jonas Nordström, et al.
Almmustuhtton: (2021-10-01)

Mathematical modelling of cell population dynamics in the colonic crypt with application to colorectal cancer
Dahkki: Johnston, M
Almmustuhtton: (2008)

An epigenetic memory at the CYP1A gene in cancer-resistant, pollution-adapted killifish
Dahkki: Samantha Carrothers, et al.
Almmustuhtton: (2025-01-01)

Nanoparticle induced cell magneto-rotation: monitoring morphology, stress and drug sensitivity of a suspended single cancer cell.
Dahkki: Remy Elbez, et al.
Almmustuhtton: (2011-01-01)