Evaluation of the therapeutic efficacy of praziquantel against schistosomes in seven countries with ongoing large-scale deworming programs

Evaluation of the therapeutic efficacy of praziquantel against schistosomes in seven countries with ongoing large-scale deworming programs

The World Health Organization (WHO) recommends periodic assessment of the therapeutic efficacy of praziquantel (PZQ) to detect reduced efficacy that may arise from drug resistance in schistosomes. In this multi-country study (2014), we assessed the therapeutic efficacy of a single oral dose of PZQ (...

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Bibliographic Details
Main Authors: B. Levecke, J. Vlaminck, L. Andriamaro, S. Ame, V. Belizario, A. Degarege, D. Engels, B. Erko, A.D. Garba, G.M. Kaatano, Z. Mekonnen, A. Montresor, P. Olliaro, O.S. Pieri, M. Sacko, S.O. Sam-Wobo, L.A. Tchuem Tchuenté, J.P. Webster, J. Vercruysse
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
schistosomiasis
Mass drug administration programs
Praziquantel
Drug efficacy
Anthelmintic resistance
Egg reduction rate
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320720300348

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http://www.sciencedirect.com/science/article/pii/S2211320720300348

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