Simultaneous Detection of Different Zika Virus Lineages via Molecular Computation in a Point-of-Care Assay

Simultaneous Detection of Different Zika Virus Lineages via Molecular Computation in a Point-of-Care Assay

We have developed a generalizable “smart molecular diagnostic„ capable of accurate point-of-care (POC) detection of variable nucleic acid targets. Our isothermal assay relies on multiplex execution of four loop-mediated isothermal amplification reactions, with primers that are de...

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Bibliographic Details
Main Authors: Sanchita Bhadra, Miguel A. Saldaña, Hannah Grace Han, Grant L. Hughes, Andrew D. Ellington
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Viruses
Subjects:
point-of-care diagnostics
isothermal nucleic acid amplification
nucleic acid computation
nucleic acid strand exchange
zika virus
mosquito
mosquito surveillance
multiplex nucleic acid detection
boolean logic-processing nucleic acid probes
Online Access:https://www.mdpi.com/1999-4915/10/12/714

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https://www.mdpi.com/1999-4915/10/12/714

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