Eribulin mesylate targets human telomerase reverse transcriptase in ovarian cancer cells.

Eribulin mesylate targets human telomerase reverse transcriptase in ovarian cancer cells.

Treatment of advanced ovarian cancer involves platinum-based chemotherapy. However, chemoresistance is a major obstacle. Cancer stem cells (CSCs) are thought to be one of the causes of chemoresistance, but the underlying mechanism remains elusive. Recently, human telomerase reverse transcriptase (hT...

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Bibliographic Details
Main Authors: Satoko Yamaguchi, Yoshiko Maida, Mami Yasukawa, Tomoyasu Kato, Masayuki Yoshida, Kenkichi Masutomi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0112438&type=printable

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