Identification of the main flavonoids of Abelmoschus manihot (L.) medik and their metabolites in the treatment of diabetic nephropathy

Identification of the main flavonoids of Abelmoschus manihot (L.) medik and their metabolites in the treatment of diabetic nephropathy

Introduction: Huangkui capsule (HKC) is made from the ethanol extract of Abelmoschus manihot (L.) Medik [Malvaceae; abelmoschi corolla] and received approval from the China Food and Drug Administration (Z19990040) in 1999. Currently, HKC is used for treatment of the patients with diabetic nephropath...

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Bibliographic Details
Main Authors: Zhipeng Diao, Hongmei Yu, Yapeng Wu, Yuanbo Sun, Haitao Tang, Mei Wang, Nan Li, Haitao Ge, Jianguo Sun, Harvest F. Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
Abelmoschus manihot (L.) medik
diabetic nephropathy
metabolism
pharmacological mechanism
flavonoids
HPLC-Q-TOF-MS/MS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1290868/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1290868/full

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