Effects of Early Initiation of High-Dose Dexamethasone Therapy on Pro-Inflammatory Cytokines and Mortality in LPS-Challenged Mice

Effects of Early Initiation of High-Dose Dexamethasone Therapy on Pro-Inflammatory Cytokines and Mortality in LPS-Challenged Mice

This study aims to explore the effects of early dexamethasone therapy at low to high doses on the survival and inflammatory responses in lipopolysaccharide (LPS)-challenged mice. We performed two-series experiments to explore the impact of early dexamethasone therapy at different doses (0.5 mg/kg, 1...

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Bibliographic Details
Main Authors: Ji-young Son, Won Gun Kwack, Eun Kyoung Chung, Sooyoung Shin, Yeo Jin Choi
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Healthcare
Subjects:
corticosteroid
dexamethasone
lipopolysaccharide
acute inflammation
sepsis
Online Access:https://www.mdpi.com/2227-9032/10/7/1247

Internet

https://www.mdpi.com/2227-9032/10/7/1247

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