In-vivo studies of targeted and localized cancer drug release from microporous poly-di-methyl-siloxane (PDMS) devices for the treatment of triple negative breast cancer

Abstract Triple-negative breast cancer (TNBC) treatment is challenging and frequently characterized by an aggressive phenotype and low prognosis in comparison to other subtypes. This paper presents fabricated implantable drug-loaded microporous poly-di-methyl-siloxane (PDMS) devices for the delivery...

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Bibliographic Details
Main Authors: S. C. Eluu, J. D. Obayemi, A. A. Salifu, D. Yiporo, A. O. Oko, T. Aina, J. C. Oparah, C. C. Ezeala, P. O. Etinosa, C. M. Ugwu, C. O. Esimone, W. O. Soboyejo
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50656-6