Antiviral efficacy against and replicative fitness of an XBB.1.9.1 clinical isolate

Antiviral efficacy against and replicative fitness of an XBB.1.9.1 clinical isolate

Summary: The emergence and spread of new SARS-CoV-2 variants with mutations in the spike protein, such as the XBB.1.5 and XBB.1.9.1 sublineages, raise concerns about the efficacy of current COVID-19 vaccines and therapeutic monoclonal antibodies (mAbs). In this study, none of the mAbs we tested neut...

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Bibliographic Details
Main Authors: Ryuta Uraki, Mutsumi Ito, Maki Kiso, Seiya Yamayoshi, Kiyoko Iwatsuki-Horimoto, Yuko Sakai-Tagawa, Masaki Imai, Michiko Koga, Shinya Yamamoto, Eisuke Adachi, Makoto Saito, Takeya Tsutsumi, Amato Otani, Shuetsu Fukushi, Shinji Watanabe, Tadaki Suzuki, Tetsuhiro Kikuchi, Hiroshi Yotsuyanagi, Ken Maeda, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Virology
Clinical microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223022241

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http://www.sciencedirect.com/science/article/pii/S2589004223022241

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