Effects of activating GABAB1 receptor on proliferation, migration, invasion and epithelial-mesenchymal transition of ovarian cancer cells

Effects of activating GABAB1 receptor on proliferation, migration, invasion and epithelial-mesenchymal transition of ovarian cancer cells

Abstract Objective This study aimed to explore the effects of activating GABAB1 receptor by baclofen on proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) of ovarian cancer cells. Results One hundred μmol/L, 200 μmol/L and 300 μmol/L were selected as low, medium and high...

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Bibliographic Details
Main Authors: Jun Gao, Yao Gao, Shixin Lin, Xia Zou, Yukai Zhu, Xintong Chen, Hong Wan, Hong Zhu
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Ovarian Research
Subjects:
GABAB1 receptor
Ovarian cancer
Epithelial-mesenchymal transition
Baclofen
G protein-coupled receptor
Online Access:http://link.springer.com/article/10.1186/s13048-020-00726-4

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http://link.springer.com/article/10.1186/s13048-020-00726-4

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