Utility of Multi-target Nested PCR and ELISPOT Assays for the Detection of Paucibacillary Leprosy: A Possible Conclusion of Clinical Laboratory Misdiagnosis

Utility of Multi-target Nested PCR and ELISPOT Assays for the Detection of Paucibacillary Leprosy: A Possible Conclusion of Clinical Laboratory Misdiagnosis

The diagnosis of paucibacillary (PB) leprosy often possesses a diagnostic challenge, especially for pure neuritic and lesser skin lesions with the zero bacillary load, requiring a sensitive and accurate diagnostic tool. We have included 300 clinically diagnosed new leprosy cases (comprising 98 PB ca...

Full description

Bibliographic Details
Main Authors: Haiqin Jiang, Ying Shi, Santosh Chokkakula, Wenyue Zhang, Siyu Long, Zhenzhen Wang, Wenming Kong, Heng Long, Limei Wu, Lihua Hu, Qiang Yao, Hongsheng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
diagnosis
PCR
nested PCR
ELISPOT
paucibacillary leprosy
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.814413/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.814413/full

Similar Items