Mutational meltdown of putative microbial altruists in Streptomyces coelicolor colonies

In Streptomyces coelicolor, a subpopulation of cells can arise that produce metabolically costly antibiotics and a division of labor that maximizes colony fitness. This study uses experimental evolution to understand the reproductive and genomic fate of these mutant cells, showing that the arising a...

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Bibliographic Details
Main Authors: Zheren Zhang, Shraddha Shitut, Bart Claushuis, Dennis Claessen, Daniel E. Rozen
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29924-y