The Use of Anhydrous Barium Hydroxide for Selective Alkylation of Dialkyloxy-<i>tert</i>-butyl-calix[4]arenes

A practical method of selective alkylation of the third hydroxyl group of disubstituted <i>tert</i>-butyl-calix[4]arenes using anhydrous barium hydroxide as a base was developed in this study. The use of this method in the synthesis of inherently chiral derivatives is shown herein.

Bibliographic Details
Main Authors: Oleksandr A. Yesypenko, Oleksandr O. Trybrat, Vitaly I. Kalchenko
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/3/1089