Stochastic modelling of a three-dimensional glycogen granule synthesis and impact of the branching enzyme.

In humans, glycogen storage diseases result from metabolic inborn errors, and can lead to severe phenotypes and lethal conditions. Besides these rare diseases, glycogen is also associated to widely spread societal burdens such as diabetes. Glycogen is a branched glucose polymer synthesised and degra...

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Bibliographic Details
Main Authors: Yvan Rousset, Oliver Ebenhöh, Adélaïde Raguin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010694