In-vitro and in-silico evidence for oxidative stress as drivers for RDW

Abstract Red blood cell distribution width (RDW) is a biomarker associated with a variety of clinical outcomes. While anemia and subclinical inflammation have been posed as underlying pathophysiology, it is unclear what mechanisms underlie these assocations. Hence, we aimed to unravel the mechanisms...

Full description

Bibliographic Details
Main Authors: Huibert-Jan Joosse, Brigitte A. van Oirschot, Sander A. A. Kooijmans, Imo E. Hoefer, Richard A. H. van Wijk, Albert Huisman, Wouter W. van Solinge, Saskia Haitjema
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36514-5