miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
miR-122 is a highly expressed microRNA in the liver. Here the authors analyse the mouse liver microRNA landscape following depletion of miR-122 and the impact that this has on its target mRNAs.
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-07786-7 |