miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression

miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression

miR-122 is a highly expressed microRNA in the liver. Here the authors analyse the mouse liver microRNA landscape following depletion of miR-122 and the impact that this has on its target mRNAs.

Bibliographic Details
Main Authors: Paul N. Valdmanis, Hak Kyun Kim, Kirk Chu, Feijie Zhang, Jianpeng Xu, Elizabeth M. Munding, Jia Shen, Mark A. Kay
Format: Article
Language:English
Published: Nature Portfolio 2018-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07786-7

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