Pathogen-driven degradation of endogenous and therapeutic antibodies during streptococcal infections

Pathogen-driven degradation of endogenous and therapeutic antibodies during streptococcal infections

Abstract Group A streptococcus (GAS) is a major bacterial pathogen responsible for both local and systemic infections in humans. The molecular mechanisms that contribute to disease heterogeneity remain poorly understood. Here we show that the transition from a local to a systemic GAS infection is pa...

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Bibliographic Details
Main Authors: Alejandro Gomez Toledo, Eleni Bratanis, Erika Velásquez, Sounak Chowdhury, Berit Olofsson, James T. Sorrentino, Christofer Karlsson, Nathan E. Lewis, Jeffrey D. Esko, Mattias Collin, Oonagh Shannon, Johan Malmström
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42572-0

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https://doi.org/10.1038/s41467-023-42572-0

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